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Stroke therapy: basic preclinical, and clinical directions. / edited by Leonard P. Miller

By: Contributor(s): Material type: TextPublication details: New York: Wiley-Liss, 1999.Description: xvi, 436 p.: ill.; 24cmISBN:
  • 0471183474
Subject(s): LOC classification:
  • RC388.5.S8569
Contents:
Contents: Basic science: Overview: Cellular and vascular pathophisiology of stroke -- Preclinical models of stroke -- Preclinical studies: Preclinical studies of glutamate receptor antagonists for the treatment of cerebral ischemia -- Aminobutyric acid agonists for neuroprotection -- Adenosine in ischemic brain injury -- Sodium and calcium channel modulators in stroke therapy -- Intracellular events associated with cerebral ischemia -- Nitric oxide: cellular and molecular pathways in stroke -- Free radicals in stroke -- Cellular inflammation in experimental ischemic stroke -- Apoptosis:DNA damage and repair in stroke -- Reparative approaches: Growth factors and other pharmacological treatments -- Clinical direction: Clinical trials for stroke: Design considerstions -- Thrombolytic treatment of thrombotic stroke -- Perioperative stroke, encephalopathy, and CNS dysfunction -- Stroke: present and future therapy.
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Includes bibliographical references and index.

Contents: Basic science: Overview: Cellular and vascular pathophisiology of stroke -- Preclinical models of stroke -- Preclinical studies: Preclinical studies of glutamate receptor antagonists for the treatment of cerebral ischemia -- Aminobutyric acid agonists for neuroprotection -- Adenosine in ischemic brain injury -- Sodium and calcium channel modulators in stroke therapy -- Intracellular events associated with cerebral ischemia -- Nitric oxide: cellular and molecular pathways in stroke -- Free radicals in stroke -- Cellular inflammation in experimental ischemic stroke -- Apoptosis:DNA damage and repair in stroke -- Reparative approaches: Growth factors and other pharmacological treatments -- Clinical direction: Clinical trials for stroke: Design considerstions -- Thrombolytic treatment of thrombotic stroke -- Perioperative stroke, encephalopathy, and CNS dysfunction -- Stroke: present and future therapy.

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