03431nam a22001577a 4500 190813b xxu||||| |||| 00| 0 eng d 9783540408437 RC280.B6.P43 Pediatric bone and soft tissue sarcomas. / edited by Alberto Pappo. New York : Springer, 2006. xiv, 240 p. : ill. ; 25 cm. Includes and bibliographical references and index . Contents: Epidemiology of bone and soft tissue sarcomas: Descriptive epidemiology of bone tumors -- Worldwide statistics -- North American statistics -- Mortality and survivorship -- Etiology of bone sarcomas -- Bone sarcomas: future directions -- Epidemiology of soft tissue sarcomas -- Pathologic and molecular techniques used in the diagnosis and treatment planning of sarcomas: Introduction -- Standard histopathology -- Cytogenetics -- Molecular genetic techniques -- Diagnostic imaging of pediatric bone and soft tissue sarcomas -- Local control issues in pediatric bone and soft tissue sarcomas: Introduction -- Initial evaluation of bone and soft tissue sarcomas -- Imaging techniques for evaluating the primary tumor -- Staging -- Criteria for evaluating treatment response -- Outcome criteria -- Biopsy of the primary lesion -- Imaging characteristics of specific tumors -- Post-treatment imaging concerns -- Radiofrequency ablation Local control issues in pediatric bone and soft tissue sarcomas: Significance of local control in pediatric sarcomas -- Background to local control modalities -- Ewing's sarcoma -- Rhabdomyosarcoma -- Non-rhabdomyosarcomatous soft tissue sarcomas -- Osteosarcoma -- Drug discovery in pediatric bone and soft tissue sarcomas using in vivo models: Introduction -- Pediatric tumor models -- General criteria for selecting appropriate models -- Expression profiles -- Criteria for selecting RMX xenografts for drugs evaluation -- Combination therapy -- Molecular targeted agents -- Combining signal transduction inhibitors -- Future directions -- Pediatric rhabdomyosarcom: biology and results of the North American intergroup rhadomyosarcoma trials: Epidemiology -- Pathology and biology of rhabdomyosarcoma -- Clinical presentation and evaluation of extent of disease -- Staging -- Prognostic factors -- Treatment -- Role of local therapies -- Multi-instititutional trials -- Management of specific tumor sites -- Other sites -- Acute and long term effects of therapy -- Outcome and therapy of relapse -- Non-rhabdomyosarcoma soft tissue sarcomas: Epidemiology/ pathogenesis -- Pathology/ molecular pathology -- Histologic classification -- Clinical presentation and diagnosis -- Prognosis factors and clinical staging -- Treatment -- Current problems and future challenges -- Fibrous and fibrohistiocytic tumors: Fibrous and fibrohistiocytic tumors -- Soft tissue fibrous tumors -- Fibroshistiocytic tumors -- So-called fibrohistiocytic tumors -- Current problems and future challenges -- Ewing sarcoma family of tumors: Introduction -- Epidemiology -- Pathogenesis -- Pathology -- Treatment -- Future development -- Osteosarcoma: Incidence -- Etiology/ Pathogenesis -- Molecular biology -- Pathology -- Clinical presentation and natural history -- Diagnostic evaluation -- Biopsy -- Staging -- Prognostic factors -- Treatment -- Surgery -- Radiation therapy -- Recurrent disease -- Future directions. Pappo, Alberto. lcc BK 6905 14405 0 0 lcc 0 0 WIUC-1 WIUC-1 2019-08-14 0 RC280.B6.P43 NURS/644/306/19 2019-08-14 00:00:00 1 2019-08-14 BK