01459cam a2200289 a 45000010008000000030004000080050017000120080041000290100017000700200015000870400023001020500015001250600019001400820022001591000022001812450184002032500012003872600041003993000033004405040051004735050495005246500030010196500041010496500031010906500025011217000023011462506770OSt20211118115449.0920710s1993    paua          001 0 eng c  a   92049751   a0812114388  aDNLM/DLCcDLCdDLC00aRS403.M34   aQD 453.2 M379p00a541.3/024/6152201 aMartin, Alfred N.10aPhysical pharmacy: physical chemical principles in the pharmaceutical sciences. /cAlfred Martin; with the participation of Pilar Bustamante and with illustrations by A.H.C. Chun.  a4th ed.  aPhiladelphia:bLea & Febiger,c1993.  aix, 622 p. :bill. ;c28 cm.  aIncludes bibliographical references and index.  aContents:: Introduction -- States of matter -- Thermodynamics -- Physical properties of drug molecules -- Solutions of nonelectrolytes -- Ionic equilibria -- Buffered and isotonic solutions -- Electromotive force and oxidation -- reduction -- Solubility and distribution phenomena -- Complexation and protein binding -- Kinetics -- Diffusion and dissolution -- Interfacial phenomena -- Colloids -- Micromeritics -- Rheology -- Coarse dispersions -- Drug product design -- Polymer science -- 0aPharmaceutical chemistry. 0aChemistry, Physical and theoretical. 2aChemistry, Pharmaceutical. 2aChemistry, Physical.1 aBustamante, Pilar.