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  <titleInfo>
    <title>Breast cancer: molecular genetics, pathogenesis, and therapeutics</title>
  </titleInfo>
  <name type="personal">
    <namePart>Bowcock, Anne M.</namePart>
  </name>
  <typeOfResource>text</typeOfResource>
  <genre authority="marc">bibliography</genre>
  <originInfo>
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      <placeTerm type="code" authority="marccountry">nju</placeTerm>
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    <place>
      <placeTerm type="text">Totowa, N.J</placeTerm>
    </place>
    <publisher>Humana Press</publisher>
    <dateIssued>1998</dateIssued>
    <dateIssued encoding="marc">1999</dateIssued>
    <issuance>monographic</issuance>
  </originInfo>
  <language>
    <languageTerm authority="iso639-2b" type="code">eng</languageTerm>
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  <physicalDescription>
    <form authority="marcform">print</form>
    <extent>xiii, 582 p. : ill. ; 26 cm.</extent>
  </physicalDescription>
  <tableOfContents>Contents: The Estrogen receptor and breast cancer -- Epidermal growth factor-related peptides and their cognate receptors in breast cancer -- The Role of fibroblast growth factors in breast cancer pathogenesis and progression -- Transforming growth factor and breast cancer -- The Insulin-like growth factor network and breast cancer -- Molecular alterations in breast cancer -- Apoptosis and the development of breast cancer -- WNT genes and breast cancer -- Hereditary breast cancer genes -- Biological functions of the BRCA1 and BRCA2 proteins -- Psychosocial issues in BRCA1/2 testing -- Nm23, breast differentiation and cancer metastasis -- Role of integrims in the development and malignancy of the breast -- Matrix metalloproteinases in the pathogenesis of breast cancer -- The Urokinase Plasminogen activation system in breast cancer -- Angiogenesis in breast cancer: role in biology, tumor progression and prognosis -- Cytogenetic approaches to breast cancer -- Current and future directions in surgical and chemotherapeutic approaches to breast cancer treatment -- Breast cancer therapy using monoclonal antibodies against epidermal growth factor receptor and HER-2 -- Towards the therapeutic targeting of matrix metalloproteinases in breast cancer -- MUC1 Mucin as a tumor antigen in breast cancer -- Aromatase inhibitors and the role of hormonal therapy in breast cancer -- Drug resistance in breast cancer -- Smoking as a risk for breast cancer -- The Estrogenicity of selected nutrients, phytochemicals, pesticides and pollutants: their potential roles in breast cancer -- </tableOfContents>
  <note type="statement of responsibility">edited by Anne M. Bowcock.</note>
  <note>Includes bibliographical references and index.</note>
  <subject authority="lcsh">
    <topic>Breast</topic>
    <topic>Cancer</topic>
  </subject>
  <subject authority="lcsh">
    <topic>Breast</topic>
    <topic>Cancer</topic>
    <topic>Genetic aspects</topic>
  </subject>
  <subject authority="mesh">
    <topic>Breast Neoplasms</topic>
    <topic>genetics</topic>
  </subject>
  <classification authority="lcc">RC280.B8.B67</classification>
  <classification authority="ddc" edition="21">616.99/449</classification>
  <relatedItem type="series">
    <titleInfo>
      <title>Contemporary cancer research</title>
    </titleInfo>
  </relatedItem>
  <identifier type="isbn">0896035603 (alk. paper)</identifier>
  <identifier type="lccn">98021525</identifier>
  <identifier type="uri">http://www.loc.gov/catdir/enhancements/fy0826/98021525-d.html</identifier>
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